Case Western Reserve University
Rajeet Shrestha, MD
Site PI
Dr. Rajeet Shrestha completed his general psychiatry residency at MetroHealth Medical Center in Cleveland, Ohio and Behavioral Neurology and Neuropsychiatry fellowship at University Hospitals Cleveland Medical Center. He specializes in neuropsychiatric disorders as well as the diagnosis and management of dementia and associated disorders. Dr. Shrestha has extensive experience in managing cognitive disorders such as Alzheimer’s disease and related dementias. He conducts clinical research studies focusing on longitudinal observation of people with cognitive concerns and clinical trials for prevention and treatment of Alzheimer’s disease.
Brian Appleby, MD
Site Co-PI
Dr. Brian Appleby is a neuropsychiatrist who treats and researches neurocognitive disorders. His clinical and research interests include prion diseases (e.g., Creutzfeldt-Jakob disease), frontotemporal lobar degeneration, and Alzheimer’s disease. Dr. Appleby received an M.D. from Georgetown University School of Medicine. He completed a psychiatry residency at Johns Hopkins Hospital, where he also completed a geriatric psychiatry fellowship. Dr. Appleby is Professor of Neurology, Psychiatry, and Pathology at Case Western Reserve University and University Hospitals Cleveland Medical Center. He is director of the National Prion Disease Pathology Surveillance Center, Medical Director of the CJD Foundation, and is Director of the Cleveland Alzheimer’s Disease Research Center’s Clinical Core and Co-Director of the Neuropathology Core. Dr. Appleby is also Chair of the Scientific Advisory Board of the Cleveland Chapter Alzheimer’s Association and a Co-PI for the Alzheimer’s Clinical Trial Consortium.
Paula Ogrocki, PhD
Site Co-PI